A SIXTEEN-ARTICLE POWERBOMB. So, nicotine leads to the up-regulation of an enzyme I wont bother to name that is beneficial to how the muscles can utilize fat for energy and how the fat cells refrain from just taking more fat in as storage. LEVITT: So, tell me what are your current feelings towards sugar? And that work ethic came from this belief that I actually dont think is that healthy. And so I do I think death is a very important part of the carbon cycle. Our staff also includes Alison Craiglow, Greg Rippin, and Corinne Wallace; our intern is Emma Tyrrell. So, if we can stop eating a few hours before bedtime, well get better sleep, our bodies will process the glucose we consume, and we can avoid Type 2 diabetes. scan a couple days later. Slow-Mag is designed to maximize mag's benefits while simultaneously minimizing its side effects. He explains the evolutionary drive to go from single-cell to multicellular life and unpacks the four different types of cell-based therapies and the problems they are attempting to solve. To listen ad-free, subscribe to Stitcher Premium. But its crazy. Sleep supplement. And so its okay to be an engineer and then to be a surgeon and then to be a McKinsey guy and then to be a nutrition guy and then to be a this guy and a that guy. But not too far behind it is cancer. So theres this molecule called adenosine. In 2014, Attia founded Attia Medical, PC, a medical practice focusing on the applied science of longevity and optimal performance. Stay tuned for Wednesdays episode Part 2 of my interview with Dr. Peter Attia! LEVITT: So can you talk about ketosis a little bit and what that means? [1][2] He is also the first person to make the round-trip swim from Maui and Lanai. So taking a bunch of people who have recovered and asking the question: what does their recovery tell us about their risk of subsequent infection relative to uninfected people? [4] First wanting to become a professional boxer, he later attended Queen's University, receiving B.Sc. Peter Attia is a physician focusing on the applied science of longevity. But I also think it wasnt that hard because I think that the life I was living was untenable. And just to be clear, Im just the guy who started it and who raises the money. I rarely have a conversation with Peter in which he doesnt introduce me to something Ive never thought about before. . Dr. Peter focuses on the applied science of longevity, the extension of human life, and overall well-being. I admire his dedication to becoming a kick-ass 100-year-old, and I only hope I can do the same! He is licensed in Texas (S8803), California (A96452), and New York (281406-1). So you took more or less the same approach to academics that you took to boxing. And this mutation actually is what saved our species, because if we didnt have the ability to go to a cold place like Europe and get fat in the fall by eating all of the fructose-rich berries, we wouldnt have survived the winters. Hes playing the long-game and working hard to maintain the strength and overall good health hell need to continue living an active and fulfilled life even when hes over 100 years old. Which diseases are killing people the most and what to do about it. ATTIA: So a big part of our clumsy response to this is that it couldnt be centrally coordinated. He is well . I think most people do get a bit of a cognitive jolt from it. Peter Attia (born 19 March 1973) is a Canadian-American physician known for his medical practice that focuses on the science of longevity. But whats more important Steve, is: whats the quality of those last 20 years? And at the time, what they said I dont know if they still say it was that if you just limit yourself to something like three hours of sleep, you get used to it and your body adjusts to it. How long? It quickly raised more than $40 million from big-name donors to facilitate expensive, high-risk studies intended to illuminate the root causes of obesity. LEVITT: And did you actually do a lot of fights? Those three effectively make up three quarters of deaths of people who dont smoke. Dr. Peter Attia. LEVITT: I cant think of many people who have reflected on their life as effectively as you have especially successful people and been able to rewrite it. Freakonomics is a registered service mark of Renbud Radio, LLC. Therapy exists to help people deal with stressors in their lives, and it can help you too. I think I probably spent too many years ignoring things that shouldnt have been ignored. Comments that attack an individual directly will be deleted. Poor, poor waitress. You can really imagine the matrix of studies that needs to be done, which says, O.K., what does transmission look like inside versus outside? ATTIA: So there were a lot of things that were really upsetting me at the time. [5] He spent two years at the National Cancer Institute (NCI) at National Institutes of Health (NIH), in Bethesda, Maryland as a surgical oncology fellow under Steven Rosenberg. And the more I learned, frankly, the less I agreed with him. When it comes to reversing the effects of Type 2 diabetes and preventing further chronic health problems, sleep is essential. So when you contrast living to 70 [and] spending 20 years in misery versus living to 75 with maybe two years in misery, it just doesnt even strike me as a trade-off. . Every time I go to an academic seminar, Im going to bring two pieces of Nicorette gum. This magnesium features what's called an enteric coating to protect it from premature disintegration. LEVITT: Yeah. Its a wonderful fuel. Thanks for listening. in mechanical engineering and applied mathematics. And these days I spend virtually no time in nutritional ketosis. Matt Hickey is the producer, and Dan Dzula was the engineer of this episode. LEVITT: Yeah, absolutely. Im involved in a coronavirus study now, that were trying to get off the ground, thats looking at the long term impact of immunity. And it was very uncomfortable. As a result, you build up fat in your liver and glucose in your blood, and that can cause a wide variety of health problems. And you said, Well, Im allergic to sugar. And with a great deal of curiosity, she said, What happens to you when you eat sugar? And you looked at her completely deadpan. And you might say, Well, gosh, thats a lot of money. But in the scope of things, thats a trivial sum of money, if we could actually know that this much fasting could extend not just life, but improve quality of life that much. We won. And I had all the time in the world. ATTIA: Well, I mean, I think it definitely has some cognitive-sharpening capacities. It was about 10 things. from Stanford University and holds a B.Sc. Steve, we should have you take the Epworth Sleep Survey. Workout and Diet. And it sucked. You sometimes need that distance from something. Dr. Peter Attia and Dr. Andrew Huberman discuss the best exercises for health and longevity.Dr. Also, I had a big fight with one of the physicians at Hopkins whos super respected and amazingly prominent. So I embarked on a sleep experiment that went on for maybe three months where I did not sleep more than three hours a night. And then at lunch we would go to the University of Toronto I grew up in Toronto so wed go to University of Torontos weight room and do our really heavy lifting. Matt Hickey is the producer, and Dan Dzula was the engineer of this episode. And I think the people who are luckiest and I put myself in that category hit local minima, recognize theyve hit a local minima, but not so much damage has been done that they cant get out of it. It was really an interesting thing to watch. This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply. ATTIA: Correct. But when we sleep, its best for our bodies to be cold when we sleep cooler, we get more rejuvenating sleep. Without your financial help, this blog is in critical danger of not surviving. And while learning to manage stress and overcome trauma may not be the only thing it takes to prevent Type 2 diabetes, it will definitely increase your odds of staying healthy longer. Peter Attia talks with Steve Levitt about the problem with immortality, whats missing from our Covid response, and why nicotine is underrated. Its not about exercising more, especially as he gets older. The short answer is, its never been deemed interesting enough to do the studies, which is great news to me, because Im 100 percent convinced this is a knowable set of answers, but someone just has to do the research. And better? The biggest risk, by the way, is probably mass vaccination. According to his website, Attia is "a Stanford/Johns Hopkins/NIH-trained physician focusing on the applied science of longevity, the extension of human life and well-being." These credentials have given Attia unparalleled clout (along with David Sinclair) in this niche of influencers. Peter Attia is the host of The Drive podcast and . We can be reached at radio@freakonomics.com. So autophagy is a very important process for preventing cancer. So you went to Stanford and got your medical degree there and then you did your residency at Johns Hopkins. Its also that it has no fiber left in it as well. As we get older, we may develop knee or hip problems, hearing or vision loss, or even memory problems. Aging often comes with significant physical problems that are increasingly tough to deal with. ATTIA: Yeah, but you have to remember, I mean, the N.I.H. Peter Attia is among the most brilliant people I've ever met, and he's succeeded in packing a life's worth of insights into this book. Thats the problem that Dr. Peter and other doctors like him are trying to solve. Because for most people, the last 20 years, especially the last 10 years, are not great, both physically and cognitively. ATTIA: So ketosis is arguably one of the most important, if not the most important, metabolic adaptation that allowed our species to survive, because our brains are so dependent on glucose. I learned so much from this conversation. So they think that you can show them something you havent done when youre done. Can you describe how you approached your undergraduate classes at Stanford? Healthspan has three pieces, right? It comes from this place of, Im not good enough. Part of the practice includes nutritional biochemistry, a field that deals with supplements. Then theres the physical piece your muscle mass function, ability to move, freedom from pain, all of those things. These things have a significant impact on our lives and on our families so how can we stay healthier longer? Now, in very low doses, which is what you would get if you were eating a piece of fruit, there is no problem in eating fructose. And so many years later, as I began to actually understand the benefits of sleep, it stands alone as one of what I think of as one of the four or five pillars of longevity. And to this day, we still respect each other greatly. He is the Co-founder and Chief Medical Officer of the fasting app Zero. My guest today is physician Dr. Peter Attia. I could basically, within two weeks, turn you into an almost-diabetic by sleep depriving you. , Almost anything youre going to eat is going to come with something thats going to slightly raise your temperature. His practice focuses on the applied science of longevity. The other two preventions, however, might surprise you, If I just took 20 guys like you and took them from eight hours a night to four hours a night for two weeks and then did these glucose tolerance tests, I could reduce [their] glucose disposal by 50%. Because theyre funding studies that have already been done, instead of funding research to be done. And we might have to take a closer look at your sleep habits. Thank you so much for joining me today! What type of a person is going to be safe in what type of an environment to go back to work? ATTIA: Now, that I remember. And tell us about the longest period of time you ever spent in ketosis. I am absolutely in the process of rewriting it, and that is my intention. Today, we have more medical knowledge than ever before. But Im not the person thats actually going to do these studies. ATTIA: What an obnoxious idiot I was. Theres a part of me this is not going to sound great Im just not an optimist when it comes to what the world is going to look like in 50 years. And I think a lot of people get there eventually in life, but I would just say, dont be afraid of that type of exploration. But not too far behind it is cancer. And so if you can say, Yeah, youll live five to seven years longer, call it 10 years longer, but at 85, youre functioning like a fit 65-year-old, thats actually a much more important win for almost everyone.. I think they often get confounded. Attia has a chapter giving advice in Tim Ferriss' book Tools of Titans. Comments deemed to be spam or solely promotional in nature will be deleted. What the three main pieces of our healthspan are. Dr. Peter focuses on the applied science of longevity, the extension of human life, and overall well-being. Its the cognitive piece so how well does your brain work as you age? If you want pasta sauce, find one that has no sugar. So I just generally say try not to eat too much before bed. If it says its got sugar in it, eat a different version. So thats how I ended up at McKinsey. LEVITT: So you love your children with a depth that is rare and I admire. Im so grateful to him for taking the time to join me here on, Healthspan has three pieces, right? One half of all Americans are on that spectrum. Dr. Peter Attia. What does it do for you metabolically? And then, of course, this third piece, which is the emotional resilience and the ability to maintain a tolerance around distress. Dr. Peter Attia. Or better yet, just cut up your own tomatoes and make your own., LEVITT: This reminds me of when we had dinner a long time ago and the waitress came up to us and asked if we had any allergies. If you pay any attention to history, we will have another pandemic that will involve yet another virus. Im sure anyone who did something at a high level, whether it be playing the piano or doing anything, once theyre so far past their prime, they look back and go, I dont think I appreciated what it took to get there.. We can be reached at. ATTIA: Exactly. About Community. LEVITT: This is not a cheap study, I imagine. ATTIA: Totally my favorite thing on the planet. I think its worth understanding that a little bit. Taubes and his cofounder,. What a complete and total travesty. His post can be found here. ATTIA: I actually this is probably one that has changed less than most in the past decade. And you would say, Peter, those seem really easy, and youd be right as a 37-year-old stud, but the point is most 60 year olds couldnt do them. . If were going to take Tylenol, we know the dose. I have used CGM extensively as a non-diabetic and correspondingly have personal experience; I am familiar with the literature cited, have considered it at great length, and have been communicating critically about the use of CGM for non-diabetics for more than a year (and warning people that it is a waste); I have followed Peter Attias career for nearly a decade, have listened to almost all of his >100 podcast episodes, was once an admirer, and am deeply familiar with his arguments about CGM; I have medical training and have nearly completed a PhD; Peter Attia once told me he respected me and offered me a job as a fact-checker (which I declined). He has since been mentored by some of the most experienced and innovative lipidologists, endocrinologists, gynecologists, sleep physiologists, and longevity scientists in the United States and Canada. Weve developed treatments for all kinds of conditions from acne to cancer, and weve greatly expanded our lifespans. People Lists Series Gifts. So I was probably averaging 28 hours of sleep a week when I was in residency. The first two are simple: Diet and exercise. ATTIA: No, I think its the hardest job. Criticism and skepticism can be far more useful than praise and unflinching belief. But theres a lot of new research coming out among economists, of all people, thats starting to flag the importance of sleep. Continuous glucose monitoring for non-diabetics: A scientifically critical FAQ. But I have to say, hes also completely, totally insane. Sign-up (free) to receive the5 Tactics in my Longevity Toolkitdelivered by email as a 5-day course. And then youd just be guaranteed to get N.S.F. So my hours from 11:00 at night until like 5:00 in the morning, in a cold apartment. [4] Steven LEVITT: If I were really sick, Peter Attia is who Id want for my doctor. Dr. Peter Attia is a physician focusing on the applied science of longevity. And these days I spend virtually no time in the past decade the... 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